im vitamin b12 injection Compounded Cyanocobalamin (Vitamin B12) Cyanocobalamin (b12) Injection 2,000 mcg/mL

28 , 644655.e4 (2018)

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Billions of injections occur across the United States healthcare systems

According to the NICE Clinical Knowledge Summary (CKS) and the British National Formulary (BNF) , the standard treatment for B12 deficiency without neurological symptoms involves: Hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks Followed by maintenance doses of 1 mg every three months For patients with neurological symptoms (such as paraesthesia, numbness, cognitive changes, or gait disturbances), more intensive treatment is required: Hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement occurs Followed by 1 mg every two months for maintenance Pernicious anaemia , an autoimmune condition where the body cannot produce intrinsic factor, requires lifelong treatment

Is there human evidence specifically for the injectable version